Tuberous sclerosis

The disease is manifested by the development of many benign tumors in various organs. Depending on the organ in which the development of tumors is observed, the clinical manifestations of the disease vary: the most characteristic are epileptic seizures, mental disorders, damage to the skin, heart, and kidneys. Sometimes the disease proceeds so outwardly not expressed (for example, with predominant damage to the heart or kidneys) that patients do not know about the disease for a long time: for example, parents do not know that they have this disease. The disease progresses, often leading to disability and reduced life expectancy. The frequency of this disease is 1: 10,000. Interestingly, in almost half of the cases, a genetic breakdown first occurs in a sick child, and is not inherited from parents.